Ongoing Clinical Research Projects
There are many active areas of research that are focused on understanding more about the disease and finding treatments that might slow the disease.
Clinical trials and clinical research projects:
1. Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis
ClinicalTrials.gov Identifier: NCT00891527
Study Hospital: Boston Children’s Hospital ( Boston, USA)
Drug Trial: Bevacizumab (Avastin) and Imatinib Mesylate (Gleevec)
Status: This study is ongoing, but not recruiting participants
Link to clinical trials. gov
2. Pilot Trial: the Safety and Feasibility of Losartan for Pulmonary Vein Stenosis
ClinicalTrials.gov Identifier: NCT02769130
Study Hospital: Hospital for Sick Children ( Toronto, Canada)
Drug Trial: Losartan
Status: This study is currently recruiting participants
Link to clinical trials. gov
3. Genetics determinants of pulmonary vein stenosis
This is a multi-institutional study that will use whole genome sequencing to understand the genetic determinants of PVS using a trios approach ( parents and affected child).
Study Hospital: Hospital for Sick Children ( Toronto, Canada) for the PVS Network
Status: This study is currently recruiting participants
Contact info: [email protected]
Clinical trials and clinical research projects:
1. Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis
ClinicalTrials.gov Identifier: NCT00891527
Study Hospital: Boston Children’s Hospital ( Boston, USA)
Drug Trial: Bevacizumab (Avastin) and Imatinib Mesylate (Gleevec)
Status: This study is ongoing, but not recruiting participants
Link to clinical trials. gov
2. Pilot Trial: the Safety and Feasibility of Losartan for Pulmonary Vein Stenosis
ClinicalTrials.gov Identifier: NCT02769130
Study Hospital: Hospital for Sick Children ( Toronto, Canada)
Drug Trial: Losartan
Status: This study is currently recruiting participants
Link to clinical trials. gov
3. Genetics determinants of pulmonary vein stenosis
This is a multi-institutional study that will use whole genome sequencing to understand the genetic determinants of PVS using a trios approach ( parents and affected child).
Study Hospital: Hospital for Sick Children ( Toronto, Canada) for the PVS Network
Status: This study is currently recruiting participants
Contact info: [email protected]